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bluesky
Joined: 20 Sep 2008 Posts: 49
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Posted: Fri Oct 03, 2008 7:36 am Post subject: Thyroid disease in pregnancy |
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Lets see if these statements are true or false
In a woman with newly diagnosed thyrotoxicosis, beta blockers can be continued through out pregnancy.
Fetal thyrotoxicosis in a euthyroid woman should be treated by maternal administration of antithyroid drugs plus thyroxine replacement.
Women with maintenance dose of carbimazole prior to pregnancy should be switched to PTU during pregnancy as it has fewer side effects.
There is an increased risk of miscarriage associated with Grave’s disease.
Treatment with PTU is known to cause IUGR.
Continuous fetal monitoring during labour is not recommended for women on PTU.
Up to 10% of thyroid nodules discovered during pregnancy can be malignant.
Radioactive iodine scan can be done in 3rd trimester if indicated |
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Hadia Koomary
Joined: 15 Sep 2008 Posts: 42
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Posted: Fri Oct 03, 2008 9:52 am Post subject: |
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| Quote: | | In a woman with newly diagnosed thyrotoxicosis, beta blockers can be continued through out pregnancy. |
False, beta bloker IUGR |
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Hadia Koomary
Joined: 15 Sep 2008 Posts: 42
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Posted: Fri Oct 03, 2008 10:01 am Post subject: Re: Thyroid disease in pregnancy |
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| bluesky wrote: | Lets see if these statements are true or false
In a woman with newly diagnosed thyrotoxicosis, beta blockers can be continued through out pregnancy.
False
Fetal thyrotoxicosis in a euthyroid woman should be treated by maternal administration of antithyroid drugs plus thyroxine replacement.
False
Women with maintenance dose of carbimazole prior to pregnancy should be switched to PTU during pregnancy as it has fewer side effects.
False
There is an increased risk of miscarriage associated with Grave’s disease.
True
Treatment with PTU is known to cause IUGR.
False
Continuous fetal monitoring during labour is not recommended for women on PTU.
False
Up to 10% of thyroid nodules discovered during pregnancy can be malignant.
False, I think less incidence.
Radioactive iodine scan can be done in 3rd trimester if indicated
False
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bluesky
Joined: 20 Sep 2008 Posts: 49
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Posted: Fri Oct 03, 2008 6:02 pm Post subject: |
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Fetal thyrotoxicosis in a euthyroid woman should be treated by maternal administration of antithyroid drugs plus thyroxine replacement.
TRUE
Up to 10% of thyroid nodules discovered during pregnancy can be malignant.
False but I think more than 10% are malignant |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Fri Oct 03, 2008 10:43 pm Post subject: Re: Thyroid disease in pregnancy |
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| bluesky wrote: | true or false
In a woman with newly diagnosed thyrotoxicosis, beta blockers can be continued through out pregnancy.
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False
Beta-blockers can be used during pregnancy to help treat significant
palpitations and tremor due to hyperthyroidism. They should be used
sparingly due to reports of impaired fetal growth associated with longterm
use of these medications. Typically, these drugs are only required
until the hyperthyroidism is controlled with anti-thyroid medications. |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Fri Oct 03, 2008 10:59 pm Post subject: Re: Thyroid disease in pregnancy |
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| bluesky wrote: | Lets see if these statements are true or false
Up to 10% of thyroid nodules discovered during pregnancy can be malignant.
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False
All thyroid nodules should be evaluated; up to 40 percent are found to be malignant. Therefore all thyroid nodules in preganncy have to be evaluated. |
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Hadia Koomary
Joined: 15 Sep 2008 Posts: 42
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Posted: Sat Oct 04, 2008 8:20 am Post subject: |
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| bluesky wrote: | Fetal thyrotoxicosis in a euthyroid woman should be treated by maternal administration of antithyroid drugs plus thyroxine replacement.
TRUE
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I think i'll agree with you as antithyroid medication will cross the placenta and can optimise fetal thyroxin level , while adminstration thyroxin to the mother will help optimise maternal thyroid hormon only as it does not cross placenta. |
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bluesky
Joined: 20 Sep 2008 Posts: 49
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Posted: Sat Oct 04, 2008 1:25 pm Post subject: |
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In maternal thyrotoxicosis complicating pregnancy neonatal hyperthyroidism doesnot occur if the mother has been euthyroid.
In maternal thyrotoxicosis complicating pregnancy an increase in the size of thyroid indicates inadequate treatment.
Neonatal goitre is a recognized complication of overtreatment. |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Sun Oct 05, 2008 2:44 am Post subject: |
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| bluesky wrote: | In maternal thyrotoxicosis complicating pregnancy neonatal hyperthyroidism doesnot occur if the mother has been euthyroid.
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False
Can still occur if TrAB is present as in Graves
Neonatal thyrotoxicosis due to persistence of maternal TRAbs occurs in about 1% of babies born to mothers with either active or previously treated Graves' disease and lasts for up to 3 months |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Thu Oct 09, 2008 8:38 pm Post subject: |
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| bluesky wrote: |
Neonatal goitre is a recognized complication of overtreatment. |
True
The goal of therapy is to keep the mother’s free T4 and free T3 levels in the high-normal range on the lowest dose of antithyroid medication.
Targeting this range of free hormone levels will minimize the risk to
the baby of developing hypothyroidism or goiter. |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Fri Oct 10, 2008 12:47 am Post subject: Re: Thyroid disease in pregnancy |
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| bluesky wrote: | Lets see if these statements are true or false
Treatment with PTU is known to cause IUGR.
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False
Potential side effects of antithyroid medications are pruritus, skin rash, urticaria, fever, arthralgias, cholestatic jaundice, lupuslike syndrome, and migratory polyarthritis.
Leukopenia -medication effect;also seen in untreated Graves' disease; WBC count before treatment is started.
Agranulocytosis is the most severe complication, but fortunately it is uncommon. |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Fri Oct 10, 2008 12:49 am Post subject: |
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| bluesky wrote: | | In maternal thyrotoxicosis complicating pregnancy an increase in the size of thyroid indicates inadequate treatment. |
False |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Fri Oct 10, 2008 1:02 am Post subject: Re: Thyroid disease in pregnancy |
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| bluesky wrote: | Lets see if these statements are true or false
Women with maintenance dose of carbimazole prior to pregnancy should be switched to PTU during pregnancy as it has fewer side effects.
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false |
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