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Sickle cell

 
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bronwyn
Century Club


Joined: 19 Jul 2006
Posts: 144
Location: Alton, Hampshire

PostPosted: Fri Jul 28, 2006 12:54 pm    Post subject: Sickle cell Reply with quote

The College seem to like Sicklers!

Quote:
A woman with Sickle cell disease comes to see you 6 weeks postnatally following an intra-uterine death at 36 weeks in her first pregnancy. Outline important aspects of your consultation.


Enjoy!
I'll post my bubbles on return from hols Cool
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Bronwyn Bell
SpR
Portsmouth
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Nick Raine-Fenning
Course Director


Joined: 27 May 2006
Posts: 1852
Location: Nottingham

PostPosted: Fri Jul 28, 2006 4:16 pm    Post subject: Reply with quote

That's an excellent question Bronwyn

They could set something like this but it may not include the medical disorder.

Lots to bubble here Shocked

Few basic points I would stress / consider:

1. counselling - lots of support / how are they coping

2. investigations and their results to date (there may have been an identifiable cause unrelated to her sickle cell such as an anomaly, pre-eclampsia, cholestasis, etc)

3. mode of delivery

4. then go with the basics:

History / Examination / Investigations / Treatment

This is a medical disorder in pregnancy question (or you can exlcude this eventuality) so you need to:

1. Assess the severity of her disease and her awareness of this

2. consideer her partners status and define the zygosity possibilities

3. discuss the effect of pregnancy on her SSD

4. briefly discuss the effect of her SSD on her pregnancy and do this for both her and her baby!

You also need to address how certain causes of stillbirth affect the next pregnancy if indeed there is to be a next one!


That's a lot of bubbles and that is the problem with Medical Disorder questions. You still have to mention all of these issues but superfiically.

Remember - you do not know where the marks are!!
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bronwyn
Century Club


Joined: 19 Jul 2006
Posts: 144
Location: Alton, Hampshire

PostPosted: Fri Jul 28, 2006 5:37 pm    Post subject: Reply with quote

Thanks Nick

Few other bubbles I had

intro
* risk of maternal morbidity with sickle crisis (?1-2.5%)
* complications more common in pregnancy (crisis complicates 35% of pregnancies)
* 4-6x increase perinatal morbidity

Relevant steps while (if) planning another pregnancy
* Contraception (risks of IUCD and prothrombotic estrogens)
* Folic acid 5mg/day
* Penicillin prophylaxis, if required, safe to continue throughout pregnancy

screening
* partner
* role and risks of CVS & amnio

Antenatal monitoring
* Hb, ferritin, HbS level, LFT, UKE monthly (renal and liver function may be compromised)
*MSU at each visit
* Possible risks of top-up exchange transfusion antenatally
* Manage infection/ dehydration aggresively
* Ultrasound for fetal assessment from 28 weeks (IUGR/ PET)
* Screen for PET antenatally
* LSCS only for obs reasons (try to avoid GA)
* continuous fetal monitoring in labour
* iron chelation agents contra-indicated in pregnancy
* May have multiple antibodies due to previous transfusions, check when cross matching (role of haematologist)
* consider thromboprophylaxis when admitted/ immobilised

I think your second point is really good...not just assuming the IUD was related to SSD

Think this questions possible too "big" in that it involves IUD, medical disorder and pre-pregnancy counselling, and as you say to keep it superficial in the little time given.

Well at least that's sickling revised in one go!

Off to Gatwick soon
Byeee Very Happy
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Bronwyn Bell
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Nick Raine-Fenning
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Joined: 27 May 2006
Posts: 1852
Location: Nottingham

PostPosted: Fri Jul 28, 2006 6:24 pm    Post subject: Reply with quote

Have a great holiday - we'll miss your contributions Sad

Back to the essay ...

Quote:
I think your second point is really good...not just assuming the IUD was related to SSD


I think this is the key point actually!

The points you mention relate more to SSD than stillbirth. In fact this is one of those questions where you could score really badly if you focused on sickle cell rather than the actual scenario. Think clinically - what would you do in real life? Therein lies the crux of this question and the key to the essays.

I would expect the marking scheme to this question would be more like the marking scheme to a stillbirth question with a twist of sickle cell rather than vice versa - that's how I would write it anyway.

It's a very interesting question / point that you raise here therefore.
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