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OHSS

 
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rpwalavalkar
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Joined: 20 Jul 2006
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PostPosted: Fri Jan 26, 2007 10:14 pm    Post subject: OHSS Reply with quote

OHSS is usually cured by aspiration of ovarian follicles Question T / F
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wolverine
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PostPosted: Fri Jan 26, 2007 10:45 pm    Post subject: Reply with quote

False. Treatment is basically supportive.
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mridulaben
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PostPosted: Sat Jan 27, 2007 10:31 am    Post subject: Reply with quote

Yes FALSE, Rx is conservative as self limited, unless severe then aspiration is indicated i think Rolling Eyes
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EMAK
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PostPosted: Sat Jan 27, 2007 1:18 pm    Post subject: Reply with quote

It is not cured but amiliorated because by aspiration we will get rid of inflamatory mediators..therefore, the condition improves....
My graetings ..Raj...
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Nick Raine-Fenning
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Joined: 27 May 2006
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PostPosted: Sat Jan 27, 2007 5:31 pm    Post subject: Re: OHSS Reply with quote

rpwalavalkar wrote:
OHSS is usually cured by aspiration of ovarian follicles Question T / F


Few important words here ...

cured - a bit like the word always in that it is almost always false! Nothing cures really Wink

Follicular aspiration (I presume they / you mean oocyte collection) does not affect the incidence or severity of OHSS. This relates to hCG and luteal support. Any pregnancy (and multiple pregnancy especially) considerably increase the risk and severity of OHSS as does the use of hCG for luteal support. It is still increased with progestogen support but less so. The best treatment is to avoid OHSS and this involves cycle cancellation prior to the administration of hCG for oocyte maturation (36 hours before oocyte collection) or not putting the embryos back if you have gone past this point. Identifying high risk patients (PCO, past OHSS, young slim women etc) and modifying their treatment protocol (low dose FSH, antagonist cycles, and now IVM) is the best treatment / prophylaxis.
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rpwalavalkar
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Joined: 20 Jul 2006
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PostPosted: Sat Jan 27, 2007 8:23 pm    Post subject: Reply with quote

a fab explaination nick, no one has an excuse for forgetting OHSS now.

by the way the answer is FALSE.
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