TEALE FENNING Medical Education    FAQ   Search   Memberlist   Usergroups   Register   Profile   Log in to check your private messages   Log in  mrcog courses for doctors IUI          TEALE FENNING Forum Index -> MRCOG Part 2: MCQ & Past Paper questions View previous topic :: View next topic   Author Message EMAK Century Club Joined: 26 Nov 2006 Posts: 570 Posted: Sat Jan 27, 2007 5:12 pm    Post subject: IUI Concerning IUI, it should only be done with washed and prepared sperms... I know this is true but can you tell me Nick the ideal way of sperm preparation..so we can achieve better result?? My Greetings... Back to top Nick Raine-Fenning Course Director Joined: 27 May 2006 Posts: 1773 Location: Nottingham Posted: Mon Jan 29, 2007 12:03 pm    Post subject: Sperm for IUI is prepared using a discontinuous density gradient which excludes many abnormal forms of sperm and most microbes from pelleting during centrifugation. We then do additional washes to get rid of seminal plasma and suspend sperm in G-fert medium (there are lots of options) which enhances capacitation. All pf these stages include antibiotics to kill off the nasty bugs in semen. By the time you get to the last wash you have around 90% highly motile sperm, much of which is hyperactivated. _________________ "Teale Fenning Medical Education" delivering evidence-based, exam-orientated learning since 1997 Back to top EMAK Century Club Joined: 26 Nov 2006 Posts: 570 Posted: Mon Jan 29, 2007 1:32 pm    Post subject: Thanks...4 care Back to top Shinelkimo Joined: 25 Apr 2007 Posts: 55 Posted: Sat Jun 02, 2007 6:59 am    Post subject: Is donor insemination increasing miscarriage rate? Why? Back to top Nick Raine-Fenning Course Director Joined: 27 May 2006 Posts: 1773 Location: Nottingham Posted: Sat Jun 02, 2007 9:13 am    Post subject: Shinelkimo wrote: Is donor insemination increasing miscarriage rate? Why? Does it? Not sure this is true. _________________ "Teale Fenning Medical Education" delivering evidence-based, exam-orientated learning since 1997 Back to top rpwalavalkar Teale Fenning Administrator Joined: 20 Jul 2006 Posts: 946 Posted: Sat Jun 02, 2007 10:27 am    Post subject: Shinelkimo, hi. the miscarriage rate does not increase. the process is same irrespective of what sperm you use. the process does not know nor does the primed endometrium, whether one has used partner's sperm or donor sperm. . all that matters is that a sperm was available and a baby was formed. i know i'm being a bit cheeky, but does that make sense? r _________________ Dr Miss. Raj Walavalkar MBBS MRCOG TealeFenning Administrator SR O&G Wessex Region Back to top EMAK Century Club Joined: 26 Nov 2006 Posts: 570 Posted: Sat Jun 02, 2007 12:27 pm    Post subject: Actually I think it is increased, I read it somewhere but can not remember where . May be it is due to the original cause of why a couple seeking IUI especialy in cases of unexplained infertility, for example when there is a uterine factor that prevent perfect implantation of Zygot due to decrease uterine blood flow.... Back to top rpwalavalkar Teale Fenning Administrator Joined: 20 Jul 2006 Posts: 946 Posted: Sat Jun 02, 2007 1:17 pm    Post subject: emak, all it takes is 1 sperm. whose sperm should not matter for conception / miscarriage. if there is a factor for miscarriage Quote: uterine factor that prevent perfect implantation of Zygot due to decrease uterine blood flow that will remain for both, partner's sperm as well as donor sperm. r _________________ Dr Miss. Raj Walavalkar MBBS MRCOG TealeFenning Administrator SR O&G Wessex Region Back to top EMAK Century Club Joined: 26 Nov 2006 Posts: 570 Posted: Sat Jun 02, 2007 3:28 pm    Post subject: Sorry I didn't see the word [Donar ] I was talking about IUI in general.sorry. Back to top rpwalavalkar Teale Fenning Administrator Joined: 20 Jul 2006 Posts: 946 Posted: Sat Jun 02, 2007 4:37 pm    Post subject: oh, ok. _________________ Dr Miss. Raj Walavalkar MBBS MRCOG TealeFenning Administrator SR O&G Wessex Region Back to top wolverine Century Club Joined: 16 Jan 2007 Posts: 393 Posted: Sat Jun 02, 2007 9:50 pm    Post subject: and what about Nick's dogma that IVF/ART increases the risk for everything? Back to top Nick Raine-Fenning Course Director Joined: 27 May 2006 Posts: 1773 Location: Nottingham Posted: Sun Jun 03, 2007 7:57 am    Post subject: wolverine wrote: and what about Nick's dogma that IVF/ART increases the risk for everything? It does but donor does not add to this. The one exception I guess is pre-eclampsia and maybe Rhesus or red cell iso-immunisation dependent on the woman's own blood group. The pre-eclampsia increase is a classic textbook fact - any 'change of partner' increases the incidence and donor sperm equates to a new partner! Back to top farha Century Club Joined: 18 May 2007 Posts: 144 Posted: Tue May 20, 2008 7:28 pm    Post subject: IUI [color=red]IUI[/color] Can be performed in UK without a licence from HFEA Live birth rate in UNEXPLAINED INFERTILITY IS more 20% iper treatment an effective treatment for oligozoospermic infertility Back to top Nick Raine-Fenning Course Director Joined: 27 May 2006 Posts: 1773 Location: Nottingham Posted: Wed May 21, 2008 7:30 am    Post subject: Re: IUI farha wrote: IUI Can be performed in UK without a licence from HFEA This used to be true and we only needed a license for IUI(D) but the new HTA now means all units need a license even for IUI alone farha wrote: IUI Live birth rate in UNEXPLAINED INFERTILITY IS more 20% iper treatment No - ~ 10/12% per cycle started and the rates vary according to the cause of subfertility and the use of gonadotrophins which increase success rates but at the expense of multiple pregnancy farha wrote: IUI Is an effective treatment for oligozoospermic infertility Absolutely but only if there are > 2-5 million motile sperm after centrifugation and sperm preparation. Most units use the 5 cut off but NICE say 2. _________________ "Teale Fenning Medical Education" delivering evidence-based, exam-orientated learning since 1997 Back to top Display posts from previous: All Posts1 Day7 Days2 Weeks1 Month3 Months6 Months1 Year Oldest FirstNewest First         TEALE FENNING Forum Index -> MRCOG Part 2: MCQ & Past Paper questions All times are GMT Page 1 of 1   Jump to: Select a forum Announcements----------------Forum AnnouncementsExam InformationCourse Announcements Examinations----------------MRCOG Part 1: EMCQsMRCOG Part 2: MCQ & Past Paper questionsMRCOG Part 2: EMQs - Extended Matching QuestionsMRCOG Part 2: Short Answer EssaysMRCOG Part 2: Objective Structured Clinical Examination - the OSCEDRCOG: the Diploma ExaminationMFFP: Membership of the Faculty of Family Planning and Reproductive Health Care of the RCOGPLAB: The Professional and Linguistic Assessment Board test General Discussion----------------Open ForumRCOG News & UpdatesThe Study Buddy SchemeKey Facts in O&GGuidelines & ProtocolsRecommended ReadingUseful WebsitesThe Market PlaceHow things work in the UKHow do you say that? Teale Fenning Courses----------------Our UK CoursesOur Overseas CoursesOur Correspondence CourseCourse AdministrationCourse FeedbackAccommodationOther Courses Training & Career Development----------------Basic Speciality Training in O&GSubspeciality Training & Special Skills ModulesAcademic TrainingResearch & AuditThe Curriculum Vitae or CVInterview SkillsMedical EducationPublication & Presentation SkillsTraining Courses, Conferences, & MeetingsThe Job MarketClinical Attachments  You cannot post new topics in this forum You cannot reply to topics in this forum You cannot edit your posts in this forum You cannot delete your posts in this forum You cannot vote in polls in this forum Powered by phpBB © 2001, 2005 phpBB Group