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EMAK Century Club
Joined: 26 Nov 2006 Posts: 572
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Posted: Fri May 25, 2007 9:43 am Post subject: Dysfunctional uterine bleeding |
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Practical tips
Dysfunctional uterine bleeding is a diagnosis of exclusion: other conditions such as uterine fibroids, endometrial polyps, and systemic diseases must be excluded by appropriate investigations
Tranexamic acid and mefenamic acid are among the most effective first line drugs for treating menorrhagia
Women needing contraception have a choice of combined oral contraceptive, levonorgestrel releasing intrauterine system, or long acting progestogens
Only 2% of endometrial carcinomas occur before age 40. Nulliparity, diabetes, obesity, and polycystic ovary syndrome are risk factors
Postmenstrual scans are often useful; the endometrium should be at its thinnest then, and polyps and cystic areas are more noticeable
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Ref: BMJ
http://www.bmj.com/cgi/content/short/334/7603/1110?etoc |
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Nick Raine-Fenning Course Director
Joined: 27 May 2006 Posts: 1854 Location: Nottingham
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Posted: Fri May 25, 2007 3:13 pm Post subject: |
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Not sure this is still true following the NICE Guideline on HMB.
The info (aimed at GPs) mentions this document is 'due' so is out of date.
Primary treatment is now the Mirena!
Have a read of this link where we have briefly started to discuss the new Guideline. _________________ "Teale Fenning Medical Education" delivering evidence-based, exam-orientated learning since 1997 |
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EMAK Century Club
Joined: 26 Nov 2006 Posts: 572
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Posted: Fri May 25, 2007 3:56 pm Post subject: |
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| Quote: | | Primary treatment is now the Mirena! |
Really? even before simple medical treatment like mefenamic acid and Cyclocapron ?
Actually I recieve this BMJ article just today. |
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Nick Raine-Fenning Course Director
Joined: 27 May 2006 Posts: 1854 Location: Nottingham
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Posted: Fri May 25, 2007 4:08 pm Post subject: |
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Yes
Read the NICE Guideline. _________________ "Teale Fenning Medical Education" delivering evidence-based, exam-orientated learning since 1997 |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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Posted: Fri May 25, 2007 4:44 pm Post subject: |
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| Quote: | Pharmaceutical treatment
• If history and investigations indicate that pharmaceutical treatment is appropriate and either hormonal or non-hormonal treatments are acceptable, treatments should be considered in the following order:
*levonorgestrel-releasing intrauterine system (LNG-IUS) provided long-term (at least 12-months) use is anticipated
*levonorgestreltranexamic acid or non-steroidal anti-inflammatory drugs (NSAIDs) or combined oral contraceptives (COCs)
*levonorgestrelnorethisterone (15 mg) daily from days 5 to 26 of the menstrual cycle, or injected long-acting progestogens.
• If hormonal treatments are not acceptable to the woman, then either tranexamic acid or NSAIDs can be used. |
Thi is current stand from NICE on HMB |
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 921
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EMAK Century Club
Joined: 26 Nov 2006 Posts: 572
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Posted: Sat May 26, 2007 6:53 am Post subject: |
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Thanks a lot
I read it previuosly and I review it with the forum and with Nick advice. |
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rpwalavalkar Teale Fenning Administrator
Joined: 20 Jul 2006 Posts: 966
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Posted: Thu Sep 04, 2008 6:44 am Post subject: |
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a quick reference list for causes guys, please add or debate causes that you don't agree with ---
ovulatory
hypothyroidism / hyperthyroidism
drug induced/medication side effects (coumadin, ASA, steroids)
coagulation disorders --
Idiopathic thrombocytopenia / septicemic thrombocytopenia / immunologic thrombocytopenia
hereditary clotting factor abnormalities --
factor VIII deficiency (von Willibrand's disease)
factor XI deficiency (Rosenthal's syndrome)
factor V deficiency (Owren's disease)
factor VII deficiency
factor X deficiency (Stuart factor deficiency)
prothrombin deficiency and dysfibrinogenemia
liver cirrhosis
hepatitis
trauma/foreign bodies
infection
severe vaginal infection (trichomonas, bacterial vaginitis, yeast)
cervicitis
anovulatory with atrophic endometrium
contraceptive associated -- DMPA / OCP / POP / Implant
increased prolactin --
pituitary prolactinoma
hyperprolactinemia
other pituitary tumors
empty sella syndrome
growth hormone excess - acromegally
Nelson's syndrome
pseudotumor cerebri
chronic renal failure/hemodialysis
persistant postpartum amenorrhea-galactorrhea
chronic systemic disease
anovulatory with proliferative/hyperplastic endometrium
stress-related
polycystic ovarian syndrome
hyperandrogenism/insulin resistance
adrenogenital syndrome
Cushing's syndrome
hypothyroidism
obesity _________________ Dr Miss. Raj Walavalkar MBBS MRCOG
TealeFenning Administrator
SR O&G Wessex Region |
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