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CVS

 
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bluesky



Joined: 20 Sep 2008
Posts: 49

PostPosted: Fri Oct 10, 2008 5:25 pm    Post subject: CVS Reply with quote

CVS is associated with higher false positive rates than amniocentesis

CVS is associated with 2% risk of miscarriage.

Regarding CVS transabdominal route has higher rate of miscarriage than transcervical route.

CVS is contraindicated in women with hepatitis C.

CVS may diagnose a chromosome abnormality not expressed in the fetus.

CVS increases the risk of limb reduction deformities.
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bluesky



Joined: 20 Sep 2008
Posts: 49

PostPosted: Sun Oct 12, 2008 10:14 am    Post subject: Reply with quote

ANSWERS:
1. False

2.True ( RCOG guideline: 3%)

3. False ( RCOG guidleine)

4.False (RCOG guidleine) Invasive testing can be done in 1st/2nd trimester in women carrying Hep B/C but limitiation of available data should be explained. testing shoud be avoided in HIV positive women particularly in 3rd trimester.

5.False

6.False ( Limb deformities are increased only if CVS is done before 10 weeks)
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Nick Raine-Fenning
Course Director


Joined: 27 May 2006
Posts: 1854
Location: Nottingham

PostPosted: Sun Oct 12, 2008 10:34 am    Post subject: Re: CVS Reply with quote

bluesky wrote:
CVS is associated with higher false positive rates than amniocentesis

CVS may diagnose a chromosome abnormality not expressed in the fetus.


I think these are both TRUE due to placental mosaicism.
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Nick Raine-Fenning
Course Director


Joined: 27 May 2006
Posts: 1854
Location: Nottingham

PostPosted: Sun Oct 12, 2008 10:35 am    Post subject: Reply with quote

bluesky wrote:
CVS increases the risk of limb reduction deformities.


This is FALSE and this is an important one to remember as many people still get this wrong on our courses.
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bluesky



Joined: 20 Sep 2008
Posts: 49

PostPosted: Sun Oct 12, 2008 11:05 am    Post subject: Reply with quote

Oops Oops

2% placental Mosaicism with CVS Crying or Very sad

Thanks Nick
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