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EMAK
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Joined: 26 Nov 2006
Posts: 572
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 Posted: Fri Jan 26, 2007 7:07 pm Post subject: Appropriate treatments for ovarian failure |
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Primary Ovarian failure: Clomiphene Citrate
Secondary Ovarian failure:HCG
Both are not a treatment for such cases.....
any other opinions.........? |
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vani s
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Joined: 20 Jan 2007
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| Posted: Fri Jan 26, 2007 7:35 pm Post subject: |
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| both false... |
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rpwalavalkar
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Joined: 20 Jul 2006
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| Posted: Fri Jan 26, 2007 9:48 pm Post subject: |
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both FALSE...
once the ovary had failed only thing left to do is ...
HRT -- for symptoms
oocyte donaation IVF -- for fertility
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Dr Miss. Raj Walavalkar MBBS MRCOG
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Nick Raine-Fenning
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Joined: 27 May 2006
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Location: Nottingham
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| Posted: Sat Jan 27, 2007 5:47 pm Post subject: |
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| rpwalavalkar wrote: | both FALSE...
once the ovary had failed only thing left to do is ...
HRT -- for symptoms
oocyte donation IVF -- for fertility |
Indeed ... do not forget adoption 
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"Teale Fenning Medical Education" delivering evidence-based, exam-orientated learning since 1997 |
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rpwalavalkar
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| Posted: Mon Apr 07, 2008 12:43 pm Post subject: |
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Side effects of clomifene citrate include increased miscarriage rate. .... T/F
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Dr Miss. Raj Walavalkar MBBS MRCOG
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salihabduallah
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Joined: 04 Sep 2007
Posts: 120
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| Posted: Mon Apr 07, 2008 2:28 pm Post subject: |
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| true as it increase fetal congenital malformation. |
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farha
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Joined: 18 May 2007
Posts: 156
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| Posted: Mon Apr 07, 2008 4:13 pm Post subject: clomiphine citrate |
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well I don, t agree ha CC increases congenital abnormaliies or miscarriage rate
refrence tog 2005 issue 1
| Quote: | Miscarriage andectopic pregnancy rates are comparable to thosein the general population,28 and there is noincreased risk of congenital
malformation withthe use of clomifene |
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Nick Raine-Fenning
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Location: Nottingham
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| Posted: Mon Apr 07, 2008 6:06 pm Post subject: |
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It's an interesting one.
I am not aware of any increase in abnormalities but all aberrant outcomes are more common after fertilit treatment and in subfertile women even if they conceive naturally. Does CC make an actual difference however?? Not sure.
It is associated with endometrial thinning which is due to its partial agonist / antagonist action so maybe this could be the link.
If I had to gamble I'd say ..... (still thinking but siding with false ) |
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rpwalavalkar
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| Posted: Mon Apr 07, 2008 7:07 pm Post subject: |
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well, i dont know what the answer is but my gut feeling was False.
then again, as fert treatment is assoc with multiple preg, may be the miscariage rate increases 
i agree with Nick over the congenital malformation not being any higher bit.
r
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Dr Miss. Raj Walavalkar MBBS MRCOG
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Xerxes I
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Joined: 01 Mar 2007
Posts: 228
Location: Winchester
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| Posted: Tue Apr 08, 2008 4:58 pm Post subject: |
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I would say False too.
Some studies have shown slight increase in miscarriage rates, others haven't (like anything else in medicine), so for the purposes of the exam, I would go for False. If it was significant, NICE would given us one of their "patients should be informed that..." statements about it. |
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cpeedahsa
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Joined: 21 Apr 2007
Posts: 921
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| Posted: Sat Apr 19, 2008 4:30 pm Post subject: Re: Appropriate treatments for ovarian failure |
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| EMAK wrote: | Primary Ovarian failure: Clomiphene Citrate
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False
Women with primary ovarian failure can be made to ovulate only under very rare circumstances.
Women with reversible ovarian failure include those with autoimmune oophoritis, who can be successfully treated with corticosteroids.
Otherwise, almost all women with primary ovarian failure fall into the category of idiopathic premature ovarian failure and cannot be made to ovulate.
In vitro fertilization (IVF) with donor oocytes is the only way they can have children. (And ofcourse adoption, fostering etc)
If Primary ovarian failure with Y chromosome then they should undergo oophorectomy to prevent tumor development. |
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