cpeedahsa Century Club
Joined: 21 Apr 2007 Posts: 922
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Posted: Tue Aug 28, 2007 11:34 pm Post subject: Anovulatory infertility in PCOS-Rx |
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Step Intervention Cost Risk of multiple gestation pregnancy
1) Weight loss (if baseline weight is elevated) Low Not increased
2) Clomiphene Low Modest increase in risk
3) Metformin alone Low Not increased
4) Clomiphene plus metformin Low Modest increase in risk
5) If DHEAS >2 mcg/mL -Clomiphene plus glucocorticoid Low Modest increase in risk
6) If DHEAS <2 mcg/mL- two month course of estrogen-progestin contraceptive followed by Clomiphene Low Modest increase in risk
7) FSH injections Resource intensive Markedly increased
8 ) Ovarian surgery Resource intensive Not increased
9) In vitro fertilization Resource intensive Markedly increased*
* This increased risk is dependent on the number of embryos transferred. |
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