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Anovulatory infertility in PCOS-Rx

 
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cpeedahsa
Century Club


Joined: 21 Apr 2007
Posts: 922

PostPosted: Tue Aug 28, 2007 11:34 pm    Post subject: Anovulatory infertility in PCOS-Rx Reply with quote

Step Intervention Arrow Cost Arrow Risk of multiple gestation pregnancy


1) Weight loss (if baseline weight is elevated) Arrow Low Arrow Not increased

2) Clomiphene Arrow Low Arrow Modest increase in risk

3) Metformin alone Arrow Low Arrow Not increased

4) Clomiphene plus metformin Arrow Low Arrow Modest increase in risk

5) If DHEAS >2 mcg/mL -Clomiphene plus glucocorticoid Arrow Low Arrow Modest increase in risk

6) If DHEAS <2 mcg/mL- two month course of estrogen-progestin contraceptive followed by Clomiphene Arrow Low Arrow Modest increase in risk

7) FSH injections Arrow Resource intensive Arrow Markedly increased

8 ) Ovarian surgery Arrow Resource intensive Arrow Not increased

9) In vitro fertilization Arrow Resource intensive Arrow Markedly increased*

* This increased risk is dependent on the number of embryos transferred.
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